Question: What Are The Symptoms Of Lithium Toxicity?

What are the side effects of stopping Lithium?

Adverse effects were the most common cause for lithium discontinuation.

Among the adverse effects, diarrhoea, tremor, creatinine increase, polyuria/polydipsia/diabetes insipidus and weight gain were the top five reasons for discontinuing lithium..

What are the most common side effects of lithium?

Common side effects of lithium can include:Hand tremor (If tremors are particularly bothersome, dosages can sometimes be reduced or an additional medication can help.)Increased thirst.Increased urination.Diarrhea.Vomiting.Weight gain.Impaired memory.Poor concentration.More items…

What time of day should lithium be taken?

Lithium is usually taken 1-3 times per day with or without food. Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks. The dose usually ranges from 600 mg to 1200 mg daily, but some people may require higher doses depending on weight or symptoms.

How long does it take to develop lithium toxicity?

Acute Lithium Toxicity Systemic symptoms are typically delayed for several hours while lithium distributes into tissues and the CNS, and initially elevated lithium levels may fall by 50-70% in this phase. Because of this, systemic and neurologic findings manifest late in acute lithium toxicity.

What organs are affected by lithium?

Lithium has adverse effects on the kidneys, thyroid gland and parathyroid glands, necessitating monitoring of these organ functions through periodic blood tests. In most cases, lithium-associated renal effects are relatively mild.

Can lithium be stopped abruptly?

If you suddenly stop taking lithium, one of the drugs most commonly prescribed to stabilize bipolar disorder moods, you can experience “rebound,” a worsening of your bipolar symptoms.

What are the symptoms of toxicity?

General symptoms of poisoning can include:feeling and being sick.diarrhoea.stomach pain.drowsiness, dizziness or weakness.high temperature of 38C (100.4F) or above.chills (shivering)loss of appetite.headache.More items…

What are the long term side effects of taking lithium?

Over the long term, lithium can cause the thyroid gland to grow (goiter) or, less often, to become underactive (hypothyroidism), which is more likely to occur in women over age 45. It can also adversely affect kidney and cardiovascular function.

What does lithium do to a normal person?

Lithium helps reduce the severity and frequency of mania. It may also help relieve or prevent bipolar depression. Studies show that lithium can significantly reduce suicide risk. Lithium also helps prevent future manic and depressive episodes.

What are the 3 main symptoms of lithium toxicity?

What are the signs and symptoms of mild to moderate lithium toxicity?Nausea and vomiting.Abdominal pain or diarrhea.Shakiness, especially in your hands.Muscle weakness.Lack of coordination of fingers, hands, arms, legs, or body.Confusion.Drowsiness.Slurred speech.More items…•

What happens when your lithium levels are too high?

Too much lithium may lead to unwanted effects such as nausea, diarrhea, shaking of the hands, dizziness, twitching, seizures, slurred speech, confusion, or increase in the amount of urine. Tell your doctor immediately if these effects occur.

How long does lithium stay in your system?

Lithium is completely absorbed in the gastrointestinal tract with peak levels occurring 0.25 to 3 hours after oral administration of immediate-release preparations and two to six hours after sustained-release preparations. A reduction in manic symptoms should be noticed within one to three weeks.

How often are lithium levels checked?

Lithium levels should be monitored after treatment has begun, and then after every dosage change if there are signs of toxicity or mood changes. Blood levels are often done five days after a dosage change as it takes some time for the levels to stabilize.

How long does it take to recover from lithium toxicity?

Patients with whole body stores and an acute ingestion (acute-on-chronic toxicity) or chronic toxicity often take days to weeks to completely recover clinically. Neurotoxicity may be irreversible after acute or chronic toxicity. Elimination half-life in toxicity varies widely (average 12.9 – 50.1 hr).

Does Lithium change your personality?

Substantial affect and mood changes are induced by lithium carbonate. Lethargy, dysphoria, a loss of interest in interacting with others and the environment, and a state of increased mental confusion were reported. No generalized effects were found in the responses to ther personality inventories.

What happens if you take lithium and not bipolar?

Lithium is still the best researched medication for this condition; no other medication has been shown to be superior in controlling depression, suicidal thoughts, or long-term mood stability. It also has been shown to decrease anger and sudden impulse decisions in people who do not have bipolar disorder.

What does lithium toxicity feel like?

The severity of lithium toxicity is often divided into the following three grades: mild, moderate, and severe. Mild symptoms: nausea, vomiting, lethargy, tremor, and fatigue (Serum lithium concentration between 1.5-2.5 mEq/L)[33] [34].

What can cause lithium toxicity?

The chronic form of lithium toxicity can occur when you take lithium daily but your serum blood level has crept up into the toxic range. 1 Possible causes for this level increase are a dosage increase, being dehydrated, interactions with other medications, and problems with kidney function.